AZ疫苗免疫反應更持久，因為棘蛋白能更長時間存在：「當你輸送的是固定量的 mRNA 分子，終究會被系統清除掉。」「但當你輸送腺病毒，你是輸送了一個持續製造mRNA的模板，接著製造棘蛋白，因此沒有所謂的上限天花板。」..
We found that transmission had the strongest association with school closure (37% reduction in Reff, 95% CI 33–40%), followed by daycare closure (31%, 95% CI 26–35%) and banning nursing home visits (26%, 95% CI 23–29%) (Fig. 3a; main model in Supplementary Tables 2, 3). Stay at home orders were associated with a 15% reduction in Reff (95% CI 13–17%) while face-mask orders were associated with an 18% reduction (95% CI 16–20%). Leisure activities closure were associated with a 14% (95% CI 11–17%) reduction in Reff, while with a 5.0% (95% CI −1.9 to 12.4%) increase when lifted in the sensitivity analysis (Supplementary Fig. 6). OLS models that included a lag-term to account for autocorrelation (termed the OLS model, an alternative approach to GEE) yielded similar regression coefficients (Fig. 3a and Supplementary Table 5). To ensure the contribution of interventions in reducing Reff when prioritizing parsimony, we fitted LASSO regression on the OLS model across a range of penalties for model complexity and found that school closure was the intervention most consistently associated with reductions in Reff (Fig. 3b). Including information on NPIs improved model performance across multiple metrics (Supplementary Tables 3, 4) (see Methods).
學校關閉最有效(37% reduction,95% CI 33–40%)
次之為孩童日托中心關閉(31%, 95% CI 26–35%)